hESC Derived Germ Cells Used as a Tool to Study Steroid Hormones Found in the Environment
Endocrine active compounds such as estradiol and testosterone can be found throughout our environment in the water supply, food and other avenues. These compounds can lead to abnormal germ cell development, infertility and disease in children. Currently a human germ cell system is unavailable for study. Human embryonic stem cell derived germ cells can be utilized to study the potential effect of EAC utilizing a metabolomics approach.